Molecular Basis of Inheritance | Digital notes

- Isolate chemical from nucleus of pus cells of owl.

-This chem. is respon. for inheritance.

Named as Nuclein.

Nuclic acid are of 2 types:-

1)DNA - is a long chain polymer of Nucleotides.

2)RNA

DNA Nucleotides:-

4 type:-

1)Deoxy adnesine Mono phosphate

2)Deoxy thymidine Mono phosphate

3)Deoxy Cytidine Mono phosphate

4)Deoxy Guanosine Mono phosphate

DNA

Nucleotide = Nucleoside + Phosphate group

Nucleoside = Sugar + N - base

N - Base:-

1) Purine = 9 membered double ring str.(At 1,3,7 and 9th, N is present.)

2)Pyrimidines = 6 membered single ring structure.(At 1,3 position, N is present.)

Deoxyribose sugar

Nucleotide:-

-At 5th no. (of sugar, phosphoester bond id form with phosphate group)

-At 1st no. (of sugar N - Glycosidic linkage is form with Nitrogen base.)

(1' -  9th) Purine

(1' - 1st) Pyramidin

-In one nucleotide at 3' - OH group is always remain free to attached to the another nucleotide k/a polynucleotide is from 5' - 3' direction.

-Another chain of polynucleotide attached anti parallel with the help of H - bond.

complete drawing